The decision to use or not use menopausal hormone therapy in women without a uterus should involve an individualized risk/benefit analysis just as it should when the uterus is present. Thus, the need for a decision on the use of hormone therapy is accelerated. When a bilateral oophorectomy is performed before natural menopause, the onset of menopausal symptoms, primarily vasomotor symptoms, genital tract atrophy, and/or a decline in sexual function, is rapid, and the symptoms are more severe. Multiple lines of evidence suggest that regimens containing both estrogen and progestogen versus estrogen alone are associated with a greater relative risk of breast cancer without additional improvement in relief of hot flashes or vaginal symptoms. Reasons to add a progestogen to an estrogen-only therapy regimen after hysterectomy include the need to reduce the risk for unopposed estrogen-dependent conditions, chief among which are endometriosis or endometrial neoplasia. When the uterus is absent, estrogen treatment is all that is needed when hot flashes and/or genital atrophic symptoms are associated with surgical or natural menopause. We conducted a literature review, including a review of current guidelines. To review postmenopausal hormone therapy for women who have undergone hysterectomy with or without bilateral oophorectomy and to make clinical recommendations regarding changes in regimens compared with those for women with their uterus in place.
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The song has since attained a cult following and is seen as the staple in a revival of interest in city pop in the late 2010s. The track " Plastic Love", which was released in 1985 as a single, became a surprise hit outside of Japan in 2017 after a YouTube upload of the song went viral. Three years later, Takeuchi and her husband Tatsuro Yamashita signed with Moon Records, and she made her comeback with her sixth studio album Variety in 1984, which was released internationally and shot her to mainstream success, and peaked at No. Takeuchi then announced she would go on a temporary hiatus in 1981, terminating her contract with RCA records. She then released four albums between 19, all of which obtained commercial success, including the 1980 album Love Songs, which became her first work to peak at No. She made her singing debut after signing with the RCA record label in 1978, with whom she released her debut album Beginning, which peaked at No. Takeuchi was born in Taisha, Hikawa district, now the city of Izumo, Shimane, and attended Keio University. Regarded as an influential figure in the city pop genre, she is one of the best-selling music artists in Japan, having sold over 16 million records, and has received several accolades. Mariya Takeuchi ( 竹内 まりや, Takeuchi Mariya, born 20 March 1955) is a Japanese singer and songwriter. 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